Advances in Nutritional Research by Hans Olaf Bang, Jørn Dyerberg (auth.), Harold H. Draper

By Hans Olaf Bang, Jørn Dyerberg (auth.), Harold H. Draper (eds.)

The 3rd quantity of Advances in dietary learn keeps the precedent set in past volumes of offering authoritative studies at the present nation of information with admire to significant issues of ongoing dietary study. This sequence is designed to be of price to investigators engaged in basic learn in addition to to these inquisitive about its software to difficulties in human and animal nutrients. This quantity includes 3 chapters on contemporary advancements in learn on inorganic parts, together with a evaluate, through F. H. Nielsen, of the proof for a demand for extra hint components; a conspectus, by means of C. E. Casey and ok. M. Hambidge, at the incidence of hint aspect deficiencies in guy; and an outline, through M. Janghorbani and V. R. younger, of latest tools of assessing the bioavailability of minerals within the nutrition. There also are 3 chapters on present themes of lipid examine. One (by F. D. Sauer) is dedicated to the cardiopathic results of definite nutritional monoenoic fatty acids, one other (by C. Galli) to the impact of vitamin on prostaglandin synthesis, and the 3rd (by H. zero. Bang and J. Dyerberg) to an research of the function of the weird polyunsaturated fatty acids present in marine oils within the prevention of ischemic middle disease.

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4. 1 . , 1978). , 1976) has led to the suggestion that a balance between the formation of these two compounds controls platelet aggregability in vivo (Moncada and Vane, 1978). Both substances have arachidonic acid as their common precursor. We were able to show that eicosapentaenoic acid, as substrate for prostaglandins regulating hemostasis, acted in a quite different way than arachidonic acid. Eicosapentaenoic acid is not converted by platelets to a potent proaggrega- a 16 Hans Olaf Bang and J~rn Dyerberg tory substance but actually inhibits platelet aggregation (Dyerberg and Bang, 1978).

1 mg Cu/day for two-and-one-half months. Her serum copper was 20 p,g/100 ml and her ceruloplasmin was undetectable. , 1974). 4. , 1972). The disorder is characterized by progressive neurologic degeneration commencing in early infancy, with the onset of convulsions at about three months and a fatal outcome in early childhood. The hair has a texture reminiscent of the steely wool of copper-deficient sheep, which gave the syndrome its name. Other features consistent with severe copper deficiency include hypothermia, bone changes, and striking abnormalities of the blood vessels.

Also remarkable is the higher intake by Eskimos of the long-chain polyunsaturated fatty acids, eicosapentaenoic (20:5n3), docosapentaenoic (22:5n3) and docosahexaenoic (22:6n3) acids. 8% in Danish food. This means that the polyunsaturated fatty acids in Eskimo food are highly dominated by acids belonging to the n3 family (the linolenic acid family), whereas the n6 family (the linoleic acid family) dominates in Danish food. This is also reflected in the serum fatty acid pattern of Greenlanders (Tables Vll, VIII, and IX).

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